Alex Aller, Ph.D., Cancer Researcher & Yachter Charter Captain
CONTACT Dr. Aller
https://www.linkedin.com/in/alex-aller-ph-d-799227175/
TRANSCRIPT
This is a transcript from The Floridaville podcast. This transcript was created using artificial
intelligence so it may not be an accurate account of what was recorded.
ROSANNA CATALANO
0:08
This is the Floridaville.
Get to know the people behind the Florida names you know. I'm your host,
ROSANNA CATALANO. On today's episode, we get to know DR. DR. ALEX ALLER, a
cancer researcher who's working on a team that's creating a cancer vaccine.
ROSANNA CATALANO
0:36
We are here in Tampa, Florida and our guest today is ALEX
ALLER. Welcome to the show.
DR. ALEX ALLER:
Thanks so much for having me, Ro. DR.
ROSANNA CATALANO
ALEX ALLER is the Director of Business Development at a
clinical stage company developing novel cell and gene therapies. Can you tell
our listeners in layman's terms what cancer is and why do some get it and
others don't?
DR. ALEX ALLER
1:00
Sure. Well, cancer as most of you know is an uncontrolled
growth of cells. It can be a breast cell, it can be a prostate
cell, it can be any cell in your body can go wild. When they grow wild and they
form a tumor, they start growing uncontrolled. And that's the problem. Cells
start to grow uncontrolled, starts with a few cells, that's not a big deal.
Once they start multiplying, and they don't stop, that's when you get a tumor
formed, or in the case of leukemia, is it takes over your blood. The problem is
that the cells are growing uncontrolled. Now, what would cause a cell to grow
uncontrolled? Well, there's really only one thing that can do that. And that is
mutations in the DNA. The DNA is what codes for all the proteins in your body
and what makes you who you are and what makes any cell what it is. So you've
got this DNA in there and it codes for all the different things that make a
cell the cell. Make you you. And what happens every now and then is you'll get
mutations in this DNA. I'll get into that in just a minute. A lot of these
mutations are just, don't do anything. Some of them will cause the cell to die.
DR. ALEX ALLER
2:00
Some of the mutations don't do anything at all, every now
and then you'll get a mutation that will cause the cell to stop dying,
basically, because most of the cells in your body are replaced fairly
regularly. So if you get a mutation that causes the cell to stop dying, that
just sits there, and maybe you get another mutation that might cause it to grow
a little. And then you get another mutation that might cause it to grow a lot.
And that's when you get a tumor, or a leukemia. We're mostly gonna talk about
tumors here today. So you get these cells that are growing uncontrolled due to
mutations in the DNA. But then the question comes, where do these mutations
come from? And how do you get the mutations? There's basically two ways for
that to happen. One is you have a natural rate of mistakes when the DNA is
being copied to make another cell for whatever it is. If you're going to make a breast cell or make
a lung cell or something else. You get a mutation or a natural rate that causes
mutations just when they're being copied. So this is an inherent natural rate
of mutations that happens because like I said,
DR. ALEX ALLER
3:00
a lot of times these mutations are corrected. We have lots
of mechanisms to correct those mutations correct the mistakes your body makes.
And but sometimes those don't work either. So every now and then you have a
natural rate of mutations in the DNA. This has been going on and every creature
forever and ever. What is the second way
that you get mutations is our environment. And this is what we're mostly aware
of what most people think about when they think about what causes cancer. You
can get mutations from the air you breathe, or the car exhaust. You can get
mutations from things you eat, or bad chemicals in anything, and your food and
your water. You can get mutations, through anything that you apply on your
skin, you can get mutations from the sun's rays on your skin. So all of these
different things that are part of your environment, will cause mutations in the
DNA. So that's the bottom line. People say what causes cancer? Well, mutations
in the DNA is the bottom line, but what causes the mutations
DR. ALEX ALLER
4:00
In the DNA? Two
things: your heredity and your environment.
ROSANNA CATALANO:
How does the immune system react to cancer?
DR. ALEX ALLER
Your immune system can recognize cancer. Immune
system recognizes cancer every day. Every
day, you're getting mutations in your DNA. And your immune system recognizes
these as foreign because they're growing, they're funny, they're growing
strange. Your immune system can come in
and attack those and destroy them. And this happens fairly regularly happens to
all of us. The immune system is
attacking the DNA.
ROSANNA CATALANO:
Tell me why some people's immune system react differently to
cancer cells?
DR. ALEX ALLER
Again, your immune system can recognize the tumors and
destroy them. Obviously, not all the time. Otherwise, we wouldn't have cancer. But
you do have an immune system and most tumors have the immune system cells or
white cells. The white cells are part of your immune system. Normally those are
called T cells, maybe if people have heard of T cells, but these are the immune
system cells that recognize cancer.
DR. ALEX ALLER
5:00
But, they don't always recognize and destroy the cancer. Almost
every tumor has these T cells in it. So now you've got an immune system that
may or may not recognize the cancer and destroy it. What are two of the things
that can make your immune system strong or weak? Again, it's two things. It's
your heredity. Some people inherit a stronger immune system than others. That's
a whole research subject, I assure you, but some people's immune system is just
naturally stronger than others. Again, the other part is your environment. Just
like the causes cancer, this causes the strength or weaken your immune system. What
could cause your immune system to be strong or weak? Okay, what can cause it to
be strong is take your vitamins, workout, do cardio, eat, right? Do the right
things to your body that we all know. What can cause your immune system to be
weak? Smoking cigarettes, sitting on the couch, eating bad food. Again, a lot
of these things are double hits, because they'll cause the cancer and they'll
also inhibit your immune response. What's about the worst thing you can do?
DR. ALEX ALLER
6:00
Smoke cigarettes. Smoking cigarettes will not only induce
the mutations, cause the cancer to go wild. But it also inhibits your immune
response. So smoking cigarettes is just about the worst. As a cancer researcher
that just freaks me out when I see people smoking cigarettes for those two
reasons. Now, what we're doing these days is we recognize that there is an
immune response to cancer. We do have
white cells in a lot of our tumors. Some of these tumors have a lot of white
cells in them. Some of them just have a few. A lot of these tumors are ongoing
necrosis, which is when the white cells are gobbling up tumor cells, but
obviously not fast enough, or you wouldn't have a tumor in the first place. So
what is happening these days in cancer research is we're looking at ways to
strengthen the immune system. We're trying to strengthen immune response. Now,
one of the problems with cancer and one of the problems that cancer does on its
own is the cancer, the tumor cells will make things that inhibit the immune
response. So the cancer actually has proteins on its
DR. ALEX ALLER
7:00
Surface, has stuff on its surface and also secrete stuff.
It's slowed down that immune response. So the cancers are not just sitting
there growing. They're not only sitting there growing, but they're recruiting
blood cells to themselves. They're also secreting proteins, secreting things
that inhibit the immune response. So you've got now, you've got these white
cells in there, but the tumor itself is causing those white cells to not do
their job. What we've done, we, the industry and other scientists, have
identified certain of these molecules on the cancer cells that stop the immune
response. These are called checkpoints, because they actually put a checkpoint,
stopping the immune response. So what we've done, once we've done identified
some of those checkpoints, now, companies have come out with checkpoint
inhibitors. So now what the main, one of the main focuses and some of the most
popular cancer drugs these days are checkpoint inhibitors. WHat they do is that they
DR. ALEX ALLER
8:00
go in and stop the checkpoint. They go in and they block the
proteins, the molecules on the surface of the tumor that cause the immune
response to not work. So now the immune response can kick back in.
ROSANNA CATALANO:
Is there a certain point in a tumors progression when it's
best to introduce a checkpoint inhibitor?
DR. ALEX ALLER
Yes, but the sooner the better. Obviously, you know, some
will grow fast and some will grow slow. Some will have a lot of white cells in
them ,some won't. The ones that are
growing fast and that have a lot of white cells in them actually are easier to
treat with this checkpoint inhibitors. So the timing of it has more to do with
the growth of the tumor and how the body is recognizing and destroying that. So
yes and no, not like there's a certain point in the tumors progression that
drugs are going to work better. You want to get any cancer as soon as you can,
and a lot of these drugs and a lot of these new checkpoint inhibitors, other
immune stimulators,
DR. ALEX ALLER
9:00
are kind of universal. So they'll do a good job, no matter
what the timing of the tumor is. Now, the problem is, some of these tumors have
a lot of white cells in them. Some of them don't. If the tumors don't have a
lot of white cells in them in the first place, they don't have an immune
response going on in the first place. And the checkpoint inhibitors aren't
going to work. Because that's not the problem. You don't have an immune
response going on. The tumor is not inhibiting an immune response, because it's
not there. Unfortunately, that's a large percent of tumors. These are what we
call cold tumors, ones that are kind of slow growing, they don't have a lot of
white cells going on in the first place. And those are what we call cold tumors. There's different ones -Pancreatic cancer
typically doesn't have that. Melanoma typically does have quite a bit of immune
system cells. And those are what we call hot tumors. So what we're trying to do
is identify patients who have those hot tumors and treat those with the
checkpoint inhibitors, because we know that those are going to work. So now we
get into
DR. ALEX ALLER
10:00
what we're looking at called biomarkers. And these are
proteins that are in the blood or stuff that's on the tumor, that you're going
to look and say, okay, yes, this patient is a good candidate for therapy. Only
working in about 20% of patients. 80%
of patients, it's not very effective, because you don't have a lot going on in
the first place. So other companies are trying to prime that immune response,
trying to start an immune response in the tumor, and then the checkpoint
inhibitors can come along and stop that tumor from inhibiting an immune
response.
ROSANNA CATALANO
How do you prime an immune response in a tumor?
DR. ALEX ALLER
10:41
Well, there's several ways to do it. And a lot of them
involve just putting stuff into the tumor itself, that will cause the tumor to
make things that will attract immune system cells. There's companies out there
that are doing that. And this is a hot field of research. Now, because now that
we have the checkpoint inhibitors, what we want to do is get that going,
DR. ALEX ALLER
11:00
get that immune response going in the first place. So we can
inject the tumors directly, or we can put stuff in the blood that will go to
the tumors and cause the immune system to start to kick in, cause white cells
to be recruited to that tumor. So that's one way to do that. That's a hot areas
of research is how do we do that? How do we start that immune response?
ROSANNA CATALANO
The research into immune response, biomarkers and checkpoint
inhibitors, are they all under the umbrella of immunotherapy?
DR. ALEX ALLER
Actually, what all this is is immunotherapy. And the beauty of immunotherapy is once you
get an immune response going, alright, say you got a melanoma on your skin, and
we can treat that we can stick stuff in it and make it cause an immune
response. Now you've got an immune response going. And so what can happen is
these white cells that are now attacking that one tumor that you treated on the
skin, those white cells can then travel throughout the body and recognize the
other tumors that have already spread to other parts of the body. So now what
you've got
DR. ALEX ALLER 12:00
is a universal immune response. You've got the white cells, first they get
going, they get going because of what we did to that tumor. And then they can
keep going, because now they're their immune system cells. It's like, if you
had a bacterial infection or something, you know, the white cells are going to
go all over the body. And now they're going to start recognizing these mets,
metastatic tumors, ones that have spread.
Your white system cells can recognize those and attack and destroy them.
Basically, that's going to be the cure for cancer. I never, ever am allowed to say the word
cure. We don't say that in research. We say treat. But I'm an optimist. And I'm
talking about further down the road. Hopefully, cancer will become a manageable
disease. Much like other diseases we have now that we're treating. Diabetes, even AIDS.
HIV is now more manageable
disease and isn't an instant death sentence.
ROSANNA CATALANO
As a lay person, we
hear the term clinical trial in reference to cancer research. Can you tell us
what that means? What are the different phases of clinical trials and who can
participate?
DR. ALEX ALLER
13:00
Yeah, sure, thank you. Um, there's essentially three phases
of clinical trials, phase one, phase two, phase three, and then you go to
commercialization. And this is all through the FDA. Because the FDA, the first
thing the FDA wants to do is make sure people are safe, make sure that these
new drugs were given are causing the disease to be worse, or killing the
patients. So phase one clinical trials, the very first time a company develops
a new therapy or new chemical or a new immunotherapy. Have to just give some to some patients that
may or may not have the disease, a lot of phase ones, people don't have the
disease. Some phase ones, they certainly do have the disease. So you give them
the new therapy, just to be sure it's safe. That's usually 6,10, 20 patients,
something like that in phase one. So this is a small clinical trial. You're not
trying to cure the patient. You're not trying to cure the disease, you're just
making sure that you don't cause any harm. Phase one by definition is do no
harm. Then you get into phase two and phase two can be
DR. ALEX ALLER
14:00
20,50, maybe 100 patients, something like that. And phase
two is where you're actually are starting to treat the disease. And that's when
you start doing dose escalations or increasing doses. And chemotherapy, you
have to be real careful, because obviously, we know chemotherapy can make
people sick and kill them by themselves. But with the new immunotherapies, now,
a lot of the immunotherapies, I've said, you know, you've inhibited, you've
augmented the immune response of some of the immunotherapies can cause autoimmune
disease, some of the immunotherapies can cause the immune system to go wild. Because now you've taken the brakes off of the
immune response. So all of these so these are things that are worked out in
phase two. Also, you can do combination therapies in phase two, like I was
talking about earlier, where you want to prime the tumor, buying the cancer,
and then attack it by stopping the inhibition of the immune response. So all
these combinations such are in phase two.
And phase three is where everybody's really trying to prove
that your new drug works and so that can be 100 to 1000 patients.
DR. ALEX ALLER
15:00
A thousands a big
number. Hundreds of patients. And again, depending on how successful it is
dependent on how safe it is, the FDA can let you go after that to
commercialization. Now one of the things
the FDA has done recently is they've got Fast Track status for some of these
drugs. These are the ones that are like the
immunotherapies that are so effective, and in general so safe, it can get
through Phase One, two and three, a lot quicker than in the past. So we got
fast track, we've got a couple other designations that will allow a company or
drug company or drug to move through these clinical trial phases very quickly.
So the FDA has really come on board. And I know a lot of people think of them
as the big bad guy who's going to stop things but actually these days, they're
helping the drugs move very quickly. Some of the administrators in the FDA are
very company friendly and doing a real good job.
ROSANNA CATALANO
You use the word quickly. I know each clinical trial is
unique but for those of us not in the industry,
ROSANNA CATALANO
16:00
can you give us an idea of an average time the clinical
process takes? Less than five years?
Yeah, less than five years. A few years, these days, a couple years. You
can go from phase one to phase two in a year. And then when you're in phase
two, and now you're starting to treat patients, you start to see really good
efficacy, like what happened with checkpoint inhibitors. And a year later,
they're in phase three a year after that their commercial. Realize that they're
different, what we call indications which are diseases so you can get a drug
approved for say melanoma. And if a checkpoint inhibitors, you get approved for
melanoma, and then you say, well, let's try head and neck cancers. Let's try
breast cancer. Let's try something else. And if it works well in those and
you've already proven safety in your phase one, phase two, man, you can get
approvals like that. Some of the new checkpoint inhibitors, one of them's made
by Merck, and it's called Keytruda. Another one's made by Bristol Myers, and
it's called up Opdivo. These things are racking up new indications every couple
of months.
ROSANNA CATALANO
17:02
Just sitting here I can see how excited you are about what
you do and the advances being made in cancer research. Everyone knows someone
impacted by cancer. Is this personal to you in some way?
DR. ALEX ALLER:
Boy, is it ever. I've watched my mother, my father and my
beautiful little sister die in my arms. It's been, it's, that's why I went
back. I went back when I was 32. To try and learn how to cure my sister. She
lived a long time. She lived a long time from that. So yeah, it's very, very
personal. My family and I were very, very close. It was just the four of us, my
mother, my father, my sister and me. And we had a wonderful life. I was always
told I could do anything and here I am out here trying to do it.
ROSANNA CATALANO:
That's amazing.
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ROSANNA CATALANO
18:05
When I met you a couple years ago, you were making a living
on the high seas as a boat captain running your own yacht charter company in
the Florida Keys. How did you go from being outside wearing flip flops in the
Florida Keys to being in an office building wearing a tie in Tampa working in
cancer research?
DR. ALEX ALLER
Well, I basically learned, started learn about immunotherapy
and I've always kind of kept my finger on it. Read a little bit, read a little
here there and I got an opportunity to come back and jumped on it.
ROSANNA CATALANO
You had mentioned that when you were 32 you went back to
school to get your doctorate. Tell us how your professional career has
meandered? Let's start at the beginning and how about you tell me where you
went to undergrad?
DR. ALEX ALLER
18:54
Okay, I went undergrad at the University of Florida.
graduated with my bachelor's degree when I was 21. I was
working in research
DR. ALEX ALLER 19:00
Then I got my master's degree, the age of 22. Having
published two papers in the American Journal of veterinary research, I've got
my masters in veterinary toxicology, studying the effects of different poisons
and how we could stop that. So then I traveled the country for several years.
So 22 year old tending bar all around the country with a master's degree in
veterinary toxicology, having spent first 20 some odd years in college, seemed
that way. So I did that, then I sold medical equipment for several years. And
when I was 32, that's when Helen developed cancer
ROSANNA CATALANO
and Helens your
sister?
DR. ALEX ALLER
Helen’s my sister. Yeah, that's when I quit my job selling
medical equipment in South Florida and moved back to Gainesville to be with my
family and go back to college. Spent the next six years in grad school, six or
seven years, a long time in grad school. And then having had the business
experience I was hired straight out of grad school to be the assistant director
of a small Cancer Research Center in Fort Lauderdale, the Goodwin Institute for
Cancer Research and
DR. ALEX ALLER
20:00
So I worked there for a few years then I worked and got
offered a job in Birmingham, Alabama at Southern Research Institute. So I went
up there and I was head of a group called Cell Biology and Immunology and
Department of Cancer Therapeutics. So we did cancer research. Then I got the
opportunity to come back as executive director of the Goodwin Institute and
really make a difference. And I did and so I moved back to cancer research for
a while.
DR. ALEX ALLER
20:25
My sister died in that period, as had my mom and my father. And
so it was just me and I was almost 50 years old, and I said, let's go do
something else. I've always made radical changes in my life. Like I say, 20
through 22 was college. 22 – 25 I was tending bar, 25 to 32 was selling medical equipment. 32 to 40 was grad school again. 40 to 50 was
cancer research. 50 was now charter boat captain and now 60 I’m back doing
cancer research. It's crazy.
DR. ALEX ALLER
21:00
I've had a lot of fun. I've never been married, never had
kids. So that's allowed me to do whatever the heck I want.
ROSANNA CATALANO
When you spoke about your family a little bit ago, you got a
little choked up. Tell us about your childhood and your parents. What was your
life like growing up? And were you a fan of science?
DR. ALEX ALLER
Oh, yeah, I was
always been a fan of Science. I love to say I was raised by Ward and June
cleaver. So those of you who don't know what that means, there was a show
called Leave it to Beaver. And every day Ward would come home and say Honey,
I'm home and the mom would be there with the two kids and that's how I was
raised. I was raised with so much love. My parents met in the seventh grade.
They were together till they died. And it was wonderful. I was raised with so
much love and so much encouragement. I was always told to do that I can do
whatever I want. So I did several times. And it was it was a wonderful way to
grow up. I always had everything I wanted. We weren't rich, but we weren't
poor. My father was an electrical engineer with Southern Bell and we just, I was
just raised with a lot of love and always around and
DR. ALEX ALLER
22:00
It was great. I, I guess the bottom line is I carry that
with me still all that confidence and the love that they instilled in me. I'm
ready to go at the drop of a hat with just about anything that I feel like I
can do. And if I can make a difference.
ROSANNA CATALANO
I can relate to that.
There's nothing like growing up in a house filled with love and being an adult
now, I can really appreciate it.
ROSANNA CATALANO
22:21
Not many people get the opportunity to step back from a
career path, go down a fork in the road, and then rejoin their original career
path. Were these career transitions easy for you?
DR. ALEX ALLER
22:33
Oh, nothing's easy. Nothing's easy. No. It's never been
easy. It's always a lot of soul searching when you're going to do something
like that. I mean, I quit a job at 49 as executive director of the Goodwin
Institute for Cancer Research to go run charters in Key West. That was quite a
DR. ALEX ALLER
22:50
thrill. And it was it was difficult, but I knew I could do
it. Like I said, just from what my
parents had always told me and what I've been taught, so you have to look at
it.
DR. ALEX ALLER
23:00
What if I don't do it? How much will I regret? What will I
look back on my life and regret not doing for me? I can't even think of
anything I regret not doing because I've just jumped on everything. I mean, you
know, made a lot of money. Lost it.
DR. ALEX ALLER
23:14
So it's always a challenge. But if the right opportunity
presents itself, you got to go for it. Because if you don't, you'll always
wonder what happened and later in life, you know, what if I'd done that, you
know, I've certainly have options that I could have taken. Best friend in high
school, ended up being the drummer in Tom Petty and tried to teach me how to
play drums and I told him, Stan, you're going to be a poor musician all your
life and I'm going to be a hotshot researcher. Now I'm a poor researcher, and
he's a hotshot musician. So I wonder what if I paid attention to Stan and played
drums? You know, I don't know. But I didn't.
ROSANNA CATALANO
Would you consider yourself an entrepreneur?
DR. ALEX ALLER
23:48
Ah, I've never made any money. I think I think that by
definition, you have to make money to be an entrepreneur, and I'm really good
at making money but I lose it. I spend it.
DR. ALEX ALLER
24:00
I’ve made poor investments.
DR. ALEX ALLER
24:02
I don't know, I think you'd have to. I think you'd have to
have made some money to be an entrepreneur. I've taken a lot of challenges, but
I've know I've made money, but I've never really kept track of it, though.
Don't think so.
ROSANNA CATALANO
24:15
Getting back to your work in cancer research, what can we
expect to see in cancer research advances in the next 5, 10 or 25 years?
DR. ALEX ALLER
It's going to explode. The reason I went back to get my
degree in immunology is once we master the immune system, we're done. That's
going to be it because the immune system and defects in the immune system are
not just cancer, but infectious diseases. Why do we get infectious disease? Because
your immune system doesn't get it. Viral,
viruses, bacteria, all of those are evading the immune system. Cancer is
evading the immune system. Everything except trauma surgery and neonates. I had
a neonate nurse corrected me when I said it's just trauma surgery. So anyway,
in cancer, we're going to continue down this immunology path. If you
look if you google current Cancer Research,
DR. ALEX ALLER
25:00
it's all immunology, it's all immunotherapy, almost. There are still some chemotherapies out there
that are being used, because a lot of these are just coming down the pipe. But
in five years, these things will be there. And once we learn how to prime the
immune response, and then stimulate the immune response, and monitor the immune
response, cancer is just going to be a manageable disease. And we're going to
be fine with it. Now you're always going to get it because remember, I told you
that you have got to get those mutations in your DNA from the environment, from
whatever. You're going to get it it's
going to start but we're going to be able to just go Oh yeah, now here look
like Star Trek. Of course I’m an optimist.
ROSANNA CATALANO
25:32
We like to end our show with a little bit of fun by asking
all our guests the same seven questions. What would people be surprised to know
about you?
DR. ALEX ALLER
25:42
My real name is Walter William Aller, Jr. Everybody knows me as Alex from the time I was
22 till now. My name has been Alex. So my legal name shocks most people.
ROSANNA CATALANO
When you have guests in town, where is your favorite place
to take them out on my boat?
ALEX ALLER
On my boat!
ROSANNA CATALANO
26:00
Well I expect an invitation.
ALEX ALLER
Let's go. Let's go.
ROSANNA CATALANO
What is the name of a book you recently read that you could
not put down? Or the name of a show you enjoyed binge watching?
ALEX ALLER
Oh, well, I all I do is read. I haven't owned a TV for 15
years. I moved out of a house 15 years ago, left the TV there and haven't had
one since. I do have a huge screen for
my Netflix, of course. Right now I'm reading a Montague and Strong which was a
detective story, except the detectives are a super powerful mage and an
immortal who has incredible strength. So
it's all sci fi. I get enough of the real world at work.
ROSANNA CATALANO
Among your close
family and friends. What are you best known for?
DR. ALEX ALLER
26:40
Oh, boy, I guess high energy, fun, nice guy, a gentlemen. I
opened doors.
ROSANNA CATALANO
26:50
We talked about your nickname being Alex, and that this is a
nickname you gave yourself. I'm used to asking people if they have a nickname
and who gave it to them. I wasn't
expecting anyone to say they gave it to themselves. But I guess that is your
answer.
DR. ALEX ALLER
27:00
I was Billy until I was in my teens, and then I was called Bill
through my teens. And when I was traveling after I got my master's degree I
traveled, I was working in a restaurant in Grand Rapids, Michigan. A guy said, what should I call you? I said,
Bill. He said, Well, I've got three Bills already. I'm going to call you
Walter. And I said, No, call me Alex. Just out of the air. And that was 40 years
ago.
ROSANNA CATALANO
If you knew you could not fail. What would you attempt?
ALEX ALLER
Cure cancer! Come on.
ROSANNA CATALANO
27:35
What are the top three things you love about living in
Florida?
ALEX ALLER:
I love the warm weather. I lived in Michigan. I don't like
cold at all. I love being out on the ocean. Obviously. Charter boat captain, I love being in the
ocean. And I love the Florida Keys.
ROSANNA CATALANO
Thank you for being on our show today. It's been an absolute
pleasure.
DR. ALEX ALLER
28:06
Thank you very much for having me, Ro.
OUTRO
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episode of The Floridaville was edited by Joy Tootle. Thank you for listening.
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